Neurobiology

 

Regulation of neurogenesis and neural differentiation; systems biology of stem cells and human developmental disorders

 

Molecular and cellular signals that assemble neural circuitry

 

Genetics of complex neurological disorders: schizophrenia, bipolar disorder, autism and related disorders
 
 
Morphogen and transcription factor regulation of cell fates and boundaries in the developing forebrain

 

Cell Signaling
 
       Medha Pathak
       Mechanobiology of neural stem cells; How cells transduce mechanical forces; Mechanically-activated ion channels; Role of Piezo1 in neural stem cell fate; Mechanical forces in neural development.

Molecular Biology

 

Molecular biology of trypanosomes, mitochondrial RNA editing, mechanisms of template-independent nucleotide recognition and transfer

 

NMR spectroscopy, DNA-binding proteins, membrane proteins, cancer

 

Nucleic acid-protein interactions and molecular dynamics, catalytic mechanisms, proteomics, virion structure

 

Structure and evolution of potassium channels and immunoglobulin super-family genes

 

Mechanisms of pre-mRNA splicing and the function of splicing enhancers in exon definition, Regulation of pre-mRNA splicing and human genetic diseases, The coupling of transcription and pre-mRNA splicing

 

Biological mass spectrometry/proteomics, ubiquitin-proteasome degradation pathways, protein complexes, posttranslational modifications, protein-protein interaction

 

3D tissue modeling, angiogenesis, tumor microenvironment

 

Bacteriorhodopsin, spectroscopy, protein crystallography

 

Protein crystallography, structure function studies, membrane proteins, bacteriorhodopsin, annexi, G protein-coupled receptors (GPCR), structure-based drug design

 

Computational Biology, Protein Structure, Protein Function

 

Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development. Emphasis on long-range protein-DNA interactions, ChIP-seq, RNA-seq, ChIA-PET, and comparative genomics

 

Gene Expression and Pathogenesis in Chlamydia Trachomatis

 

Biochemistry, Chemical Biology, Structural Biology, Microbiology

 

Regulation of gene expression by LEF/TCF - beta-catenin complexes

 

Bioorganic chemistry, chemical biology, protein engineering, molecular biology and biochemistry

 

Host-associated microbial communities, metabolomics, metagenomics, microbial ecology, phage, fermentation, polymicrobial infection, microbial interactions, human microbiome
 
Quantum mechanical and molecular dynamics simulations for complex systems

Mathematical Biology

 

Theoretical analysis and practical application of Adaptive Finite Element Methods (AFEMs)

 

Computational and systems biology, including modeling of signal transduction, gene and protein networks, and stochastic systems

 

Partial Differential Equations and Applied (Functional) Analysis

 

Mathematical biology: modeling of cancer initiation and progression, dynamics of DNA transcription and repair, modeling of learning and evolution of language

 

Microstructured Materials, Multiphase Flows, Crystal Growth, Nanostructure Patterning, Metallic Alloys, Tumor Growth, Tissue Engineering

 

Computational Biology, Developmental and Cell Biology, Numerical Analsis, Interface Dynamics in Materials and Fluids, High-Performance Computing, Modeling and Simulation of Tissue Patterning, Systems Biology
 
        Andrew Noymer
        Demography; mathematical models of disease transmission at the population level; epidemiology; mathematical models of social phenomena.
 
Applied mathematics, applied probablility, stochastic differential equations

 

Applied Mathematics, Solid Mechanics, Resource Economics, Biomathematics

 

Analysis and Modeling of Reaction-Diffusion-Advection Fronts, Stochastic Partial Differential Equations, Asymptotics and Computations, Multiscale Analysis of Partial Differential Equations and Applications, Mathematical Modeling in Speech and Hearing Sciences.

 

The Level Set Method, Moving Interface and Free Boundary, Image Processing and Computer Graphics, Time Reversal and Wave Propagation, Domain Decomposition

General Biology

History and philosophy of biology

Functional Genomics

 

Single molecule dynamics, bioinformatics, functional genomics, surface plasmon resonance

 

Growth factor signaling and functional genomics in Xenopus and zebrafish, stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling

 

Functional and evolutionary genomics: gene regulation and evolution of eukrayotic sex chromosomes
 
 
Microenvironmental regulation of epithelial stem cell function in single cell resolution during normal tissue homeostasis and cancer
 
Dennis Kibler
Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Computational Analysis of Genomes / Gene Regulation / Motif Discovery / Gene Expression Clustering

 

Quantitative and population genetics, genetic basis of quantitative variation for different phenotypes in different organisms, gene mapping and microarray analysis

 

Regulation of growth factor signaling in patterning, regeneration, and oncogenesis, Mechanisms of late onset neurodegeneration

 

Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development. Emphasis on long-range protein-DNA interactions, ChIP-seq, RNA-seq, ChIA-PET, and comparative genomics

 

Structural evolutionary genomics and evolution of the expression network

 

Genomics of post-transcriptional gene regulation, mRNA processing, cancer

 

Host-associated microbial communities, metabolomics, metagenomics, microbial ecology, phage, fermentation, polymicrobial infection, microbial interactions, human microbiome
 
Computational Biology, Bioinformatics, Genomics, Neural Computation, and Machine Learning
2011 News. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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