News

Establishment of the MathBioSys Center on Multiscale Cell Fate

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The MathBioSys Center on Multiscale Cell Fate is being initiated with $10 million in funding, half from the National Science Foundation and half from the Simons Foundation. It will support research at the interface of mathematics and biology with implications for regenerative medicine, tissue engineering, birth defects and aging.  Read More...

Establishment of the UCI Center for Cancer Systems Biology

cancersystems bioFueled by a $10 million, five-year National Cancer Institute grant, Marian Waterman, John Lowengrub and Arthur Lander have established the UCI Center for Cancer Systems Biology. It’s among just 13 research institutions nationwide that are part of the NCI’s Cancer Systems Biology Consortium.  Read More...

CCBS Opportunity Award Competition 2018

Cell states and transitions

This means research into what defines cell types and states; why states are stable; how transitions among different states are normally controlled, or can be deliberately engineered; dynamic or stochastic aspects or cell states; theories of state transitions; or any other topic related to the meaningful individuality of cell “types.” 

Deadlines:

  • Step I:  Before 12:30 PM on Sunday, March 25th, hand in (or email to Karen Martin) a one paragraph abstract (can even be handwritten) briefly describing the nature of the project.
  • Step II:  Send a more complete description (up to three pages) by email by Monday, April 9th, to: kymartin@uci.edu

 

2018 Opportunity Awards

Congratulations to the winners of this year's CCBS Opportunity Awards competition based on the theme of Cell States and Transitions! Each winning proposal will receive $10,000 to be shared between the faculty for lab project expenses; and a $1,000 award for research supplies to be shared between student and/or postdoctoral participants. We look forward to hearing about the projects at next year's annual CCBS retreat scheduled March 29 - 31, 2019 at the Sheraton Universal in Los Angeles!

Title
Participants
Department(s)
Characterizing the Transition Between Naïve and Primed States of Pluripotent ESCs in Different Mammalian Species Christina Wilcox, Kate Williams PI - Ali Mortazavi Developmental & Cell Biology
Linh Vuong, PI - Peter Donovan Developmental & Cell Biology
Transcriptomic analysis of MCF-10A mammary epithelial acini in normal and invasive states Sorena Rahmanian, PI - Ali Mortazavi Developmental & Cell Biology
Qingda Hu, PI - Elliot Botvinick Biomedical Engineering and Surgery
Understanding cellular state transitions in the mammary gland microenvironment from a control theory perspective Kevin Nee, PI - Kai Kessenbrock Biological Chemistry
Suoqin Jin, PI - Qing Nie  Mathematics and Developmental & Cell Biology
Transitional states regulating macrophage heterogeneity in dystrophic muscle Nick Pervolarakis, Quy Nguyen, PI - Kai Kessenbrock Biological Chemistry
Jenna Kastenschmidt, PI - S. Armando Villalta  Physiology & Biophysics
Methylation pseudotime: a novel tool for observing protein-DNA interactions Julien Morival, PI - Tim Downing Biomedical Engineering
Adam MacLean, PI - Qing Nie  Mathematics  and Developmental & Cell Biology 
Label-free, non-destructive determination of cell state using high throughput characterization of cell physical properties Matt Bovyn, PI - Jun Allard Physics and Astronomy and Mathematics
Cody Combs, PI - Zuzanna Siwy Physics and Astronomy
Optimal experimental design for feedback models of hematopoiesis Luis Martinez-Lomeli, PI - Babak Shahbaba/Volodymyr Minin Statistics
Abdon Iniguez, Shuxiong Wang, PI - John Lowengrub  Mathematics, Biomedical Engineering and Chemical Engineering & Material Science
Prasanthi Tata, PI - Richard Van Etten Hematology/Oncology, Department of Medicine

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