Directed and Scaleable Evolution

Ravikumar Liu 768x523

In a study published November 8, 2018 in the journal Cell, CCBS associated researchers, Chang Liu and Arjun Ravikumar,  reported that they have accelerated and simplified directed evolution by having live cells do most of the heavy lifting. By inserting a specially engineered DNA replication system into yeast, the scientists were able to coax selected genes to rapidly and stably mutate and evolve as the host yeast cells reproduced. 

 

2011 Directed and Scaleable Evolution. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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