Summer 2014 in Chang Liu's Lab

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See the youtube video below about how one talented Orange County high school student spent his summer working with Dr. Chang Liu (Department of Biomedical Engineering/CCBS).
 
 
 

Broad Institute Computational Genomics Workshop

Broad CCCbanner-2014The Center for Cell Circuits is hosting an outreach computational genomics workshop at the Broad Institute, Cambridge, MA, for 2 days on September 22nd and 23rd. The workshop is aimed at reaching out to the external community and educating attendees on computational tools developed to analyze genome-scale data sets at multiple levels and to reconstruct cell circuit models from these large scale data sets. Day 1 is a lecture series followed by a limited capacity hands-on training the second day. In order to attend Day 2, attendees must go to Day 1 lecture series.

This workshop is open to everyone in the academic community (faculty, staff, post-doc fellows, PhD candidates) and has no registration costs. Travel grants are available for attendees to help cover costs.

Registration through website link below: http://www.broadinstitute.org/collaboration/cegs/outreach_workshop

 

 

High-school student Kevin Lee wins 2nd Place at the 2014 Intel STS Finalist

Kevin LeeCongratulations to University High School student Kevin Lee from Ivine on winning 2nd Place at the national 2014 Intel Science Talent Search (STS) competition for his project entitled "Electromechanical modeling of the heart in moving domains using the phase-field method." Kevin was mentored by UCI professor John Lowengrub (CCBS/Math/BME/ChEMS). He will receive a $75,000 scholarship.

Kevin's project focuses on the development of a new theory of the heartbeat through a system of partial differential equations. Cardiac arrhythmias are the leading cause of death in the industrialized world but are not well-understood due to difficulties in linking the physical beating motion of the heart with the propagation of electric signals, and vice versa.

This work successfully couples the mechanical and electrical dynamics and develops an algorithm that enables much more efficient simulations of the heartbeat than those in use today. The added insights from the model promise to improve our understanding of fatal heart conditions and ultimately aid in their treatment and prevention.

Article of the Month: Noise Attenuation

ACS coverart2 

 

This month's featured research paper is the cover article published by Meng Chen, Liming Wang, Chang C. Liu and Qing Nie from UCI in the October issue of ACS Synthetic Biology entitled: "Noise Attenuation in the ON and OFF States of Biological Switches." The paper describes a new theory for attenutating noise in biological systems. In the accompany- ing podcast Professor Nie discusses the paper's findings and impact.

 QNie

 

News - September 30, 2013

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CCBS associated faculty member, Ali Mortazavi from the Department of Developmental and Cell Biology has been named a recipient of the prestigious 2013 National Institutes of Health Director's New Innovator Awards. The highly selective award program supports projects by early-career researchers that show potential to transform scientific fields and accelerate the translation of research into new ways to improve human health. His project will explore how DNA codes the precise activities of genes involved with development. His lab will create methods to measure how this gene expression is affected by changes in the organization of DNA in embryonic stem cells as they differentiate into neurons and cardiac muscle cells. Mortazavi believes his research will identify fundamental principles of gene regulation as well as the specific DNA elements critical to stem cell differentiation.
2011 News. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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