Developmental Biology



Drosophila development, TGF-beta signal transduction, cell signaling


Molecular embryology, molecular biology, developmental biology, functional genomics, endocrinology, pharmacology, high-throughput screening


Regulation of neurogenesis and neural differentiation; systems biology of stem cells and human developmental disorders


Growth factor signaling and functional genomics in Xenopus and zebrafish, stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling


Systems biology of cell differentiation. Using a combination of theoretical and experimental approaches to find out how regulatory networks control the progression from a stem cell state to a differentiated state.


Effect of exercise on gene and protein expression of key inflammatory and growth mediators in peripheral blood mononuclear cells in health children


Limb regeneration; dedifferentiation; pattern formation


Cardiovascular modeling: development and function at the cellular, tissue and organ level
Molecular basis of genetic diseases in humans


Systems biology of morphogenesis and pattern formation, growth control, proteoglycans, extracellular matrix, birth defects syndromes


Regulation of growth factor signaling in patterning, regeneration, and oncogenesis, Mechanisms of late onset neurodegeneration


Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Systems Biology / Scientific Inference Systems / Mathematical Methods


Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development. Emphasis on long-range protein-DNA interactions, ChIP-seq, RNA-seq, ChIA-PET, and comparative genomics
       Medha Pathak
       Mechanobiology of neural stem cells; How cells transduce mechanical forces; Mechanically-activated ion channels; Role of Piezo1 in neural stem cell fate; Mechanical forces in neural development.
Stem cells and stem cell niche, regeneration of tissues and organs, biological pattern formation, self-organization, skin and hair follicles, adipose tissue, WNT and BMP signaling pathways
Zebrafish development, pattern formation, morphogenesis


Genetic and epigenetic programing; functions of long range non-coding RNAs


Drosophila development, regulation of nuclear position and migration, effects of proteoglycans in growth factor signaling, regulation of developmental gene expression.
Experimental and computational approaches to studying the regulation of gene expression, Drosophila development, interpreting natural variation in regulatory sequences
2011 Developmental Biology. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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