Developmental Biology

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Drosophila development, TGF-beta signal transduction, cell signaling

 

Molecular embryology, molecular biology, developmental biology, functional genomics, endocrinology, pharmacology, high-throughput screening

 

Regulation of neurogenesis and neural differentiation; systems biology of stem cells and human developmental disorders

 

Growth factor signaling and functional genomics in Xenopus and zebrafish, stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling

 

Systems biology of cell differentiation. Using a combination of theoretical and experimental approaches to find out how regulatory networks control the progression from a stem cell state to a differentiated state.

 

Effect of exercise on gene and protein expression of key inflammatory and growth mediators in peripheral blood mononuclear cells in health children

 

Limb regeneration; dedifferentiation; pattern formation

 

Cardiovascular modeling: development and function at the cellular, tissue and organ level
 
Molecular basis of genetic diseases in humans

 

Systems biology of morphogenesis and pattern formation, growth control, proteoglycans, extracellular matrix, birth defects syndromes

 

Regulation of growth factor signaling in patterning, regeneration, and oncogenesis, Mechanisms of late onset neurodegeneration

 

Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Systems Biology / Scientific Inference Systems / Mathematical Methods

 

Applications of genomics, computation, and sequencing technologies to the analysis of transcriptional regulation in development. Emphasis on long-range protein-DNA interactions, ChIP-seq, RNA-seq, ChIA-PET, and comparative genomics
 
       Medha Pathak
       Mechanobiology of neural stem cells; How cells transduce mechanical forces; Mechanically-activated ion channels; Role of Piezo1 in neural stem cell fate; Mechanical forces in neural development.
 
Stem cells and stem cell niche, regeneration of tissues and organs, biological pattern formation, self-organization, skin and hair follicles, adipose tissue, WNT and BMP signaling pathways
 
Zebrafish development, pattern formation, morphogenesis

 

Genetic and epigenetic programing; functions of long range non-coding RNAs

 

Drosophila development, regulation of nuclear position and migration, effects of proteoglycans in growth factor signaling, regulation of developmental gene expression.
 
Experimental and computational approaches to studying the regulation of gene expression, Drosophila development, interpreting natural variation in regulatory sequences
2011 Developmental Biology. Copyright © 2013. The Center for Complex Biological Systems, UC Irvine
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