Speaker: Pieter Derdeyn (PI: Kevin Beier) Title: Circuit Organization of Ventral Tegmental Area Revealed by Input-Output Tracing and Dimensional Reduction Abstract: In the past few decades, evidence has revealed the remarkable complexity of the midbrain dopamine (DA) system. The DA cells are located in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNc),…

Meeting ID: 975 2123 3383 Passcode: 123679     Computational and Image Analysis Techniques for Quantitative Evaluation of Striated Muscle Tissue Architecture Advisor: Anna Grosberg (BME) Quantitative evaluation of cellular morphology is crucial to understanding development and pathology of striated muscle tissues, including skeletal and cardiac myocytes. Striated myocytes are composed of parallel myofibrils, which are spanned…

Speaker: Yingxin Cao PIs: Xiaohui Xie & Qing Nie Title: Scalable and Accurate Invariant Representation Learning for Single-Cell ATAC-Seq Processing and Integration Abstract: Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) provides new opportunities to dissect epigenomic heterogeneity and elucidate transcriptional regulatory mechanisms. However, computational modelling of scATAC-seq data is challenging due to its high dimension,…