Richard Van Etten

Richard Van Etten
Professor & Director, Chao Family Comp. Cancer Center
124 Sprague Hall
 

Richard Van Etten, M.D., Ph.D., is a Professor of Medicine and Biological Chemistry and the Director of the Chao Family Comprehensive Cancer Center at UCI. Dr. Van Etten has been involved in basic and translational cancer research for over 25 years as a faculty member at academic medical centers, initially at the Dana-Farber/Harvard Cancer Center and subsequently at Tufts University. He currently serves as a regular member of NCI Cancer Centers Subcommittee A. He is also a member of the Leukemia Committee of the Eastern Cooperative Oncology Group/ACRIN. His lab studies the molecular pathogenesis of human leukemia with a heavy emphasis on modeling these diseases in laboratory mice using retroviral/lentiviral gene transfer and bone marrow transplantation, and using conditional transgenic mouse technology. He has extensive experience in murine hematopoietic stem cell transplantation and in the analysis of healthy and diseased BM chimeric mice. Dr. Van Etten’s group has modeled adoptive immunotherapy of chronic myeloid leukemia (CML) and B-cell acute lymphoblastic leukemia (B-ALL), discovered novel signaling pathways in CML and B-ALL, and tested new approaches to targeted therapy of myeloid and lymphoid leukemia. Dr. Van Etten also a clinician specializing in hematologic malignancies, currently caring for many CML patients in various phases of the disease, and serving as institutional co-investigator on multiple clinical trials in blood cancer.