Robert A. Edwards, M.D., Ph.D., is an Associate Professor in the Department of Pathology & Laboratory Medicine. Dr. Edwards is the Director of the Experimental Tissue Resource (ETR) within the Chao Family Comprehensive Cancer Center. Research in his laboratory is focused on understanding how chronic inflammatory signals in the intestine promote colorectal cancer (CRC). As a Pathology resident and post-doctoral fellow, he studied a new mouse tumor model that links inflammation and colon cancer, via knockout of the G-protein subunit Gαi2. Upon establishing his laboratory at UC Irvine, he developed collaborations with Dr. Steve Lipkin and MPI Waterman to study how this mouse model connects to human colon cancer. For the past 10 years, his work has highlighted network links between inflammation, hypoxia, Wnt and Notch signals in the tumor microenvironment, both in animal models and in clinical isolates of human CRC.