Course Directors
The course directors are:
Germán A. Enciso, Ph.D.
Dr. Enciso is a Professor in the Department of Mathematics. Originally trained as a pure mathematician, he has extensive experience collaborating in systems biology, working on signal transduction, multisite modifications, cancer progression, cell cycle regulation, neuroscience, and cellular decision making in Chlamydia. He has a joint appointment in the Department of Developmental and Cell Biology, and he is currently supported for research in mathematical and computational biology by NSF, and NIH.
Arthur D. Lander, M.D., Ph.D.
Dr. Lander is the Donald Bren Professor of Developmental and Cell Biology, director of the NIGMS-funded Center for Complex Biological Systems (CCBS), UCI’s National Center for Systems Biology, and co-director of a newly NCI-funded National Center for Cancer Systems Biology. Originally trained as a neurobiologist and developmental biologist, his research over the past 15 years has focused on the systems biology of morphogenesis and growth. Using vertebrate and invertebrate model systems, as well as mathematical and computational modeling, he has pursued questions about pattern formation, tissue and organ size control, cancer, and the origins of syndromic and non-syndromic birth defects. He has 15 years of experience as director of T32 training grants (3 total; one current), 8 years of service as Chair of Developmental and Cell Biology, and 15 years as director of CCBS. He also holds joint appointments in the Departments of Biomedical Engineering and Logic & Philosophy of Science, and is a member of the Science Board of the Santa Fe Institute, a long-standing bastion of interdisciplinary science in the U.S. Dr. Lander has served as chair of an NIH Developmental Biology study section, member of an NICHD branch review panel, and as chair of the MABS (modeling and analysis of biological systems) NIH study section, which specializes in the review of interdisciplinary applications at the intersection between biology, engineering, mathematics and computer science.
Course faculty include Dr. Enciso and Dr. Lander, as well as a diverse group of other UCI faculty members who will oversee lectures and lab modules, and serve as post-course mentors
Course Instructors
| Instructor | Department affiliation (primary, secondary ) | Areas of Expertise |
|---|---|---|
| Jun Allard | Physics, Mathematics | Biophysics, mathematical modeling, biomechanics, cell biology |
| Bogi Anderson | Biological Chemistry, Medicine | Transcriptional regulation in normal and diseased epithelia |
| Scott Atwood | Developmental & Cell Biology | Cancer initiation, cell fate specification |
| Lee Bardwell | Developmental & Cell Biology | Cell signaling, MAP kinase pathways, mathematical modeling |
| Anne Calof | Anatomy & Neuro-bio, Dev. & Cell Bio. Opthalmology | Developmental biology, growth control, regeneration, stem cells, neural development, birth defects, mouse embryology |
| Ken Cho | Developmental & Cell Biology | Developmental Biology, Xenopus embryology, BMP signaling, gene-regulatory networks |
| Olivier Cinquin | Developmental & Cell Biology | Developmental Biology, C. elegans germline, Notch signaling, lifespan and aging, image analysis |
| Michelle Digman | Biomedical Engineering | Fluorescence fluctuation microscopy, imaging, particle tracking, biophysics |
| Tim Downing | Biomedical Engineering | Stem cell and tissue engineering, regenerative biology, epigenomcis, mechanobiology |
| Charless Fowlkes | Computer Science | Image analysis, machine learning, spatiotemporal atlases of gene expression in Drosophila |
| Enrico Gratton | Biomedical Eng., Physics , Dev. & Cell | Biophysics, optics, fluorescence fluctuation microscopy, particle tracking, theory. |
| Chang Liu | Biomedical Eng., Chemistry | Synthetic biology; engineered genetic systems for rapid evolution; chemical biology |
| John Lowengrub | Mathematics, Biomedical Eng. | Multi-scale mathematical modeling, biomechanics, tissue morphogenesis |
| Eric Mjolsness | Computer Science, Mathematics | Computational biology, plant biology, software development for mathematical biology. |
| Ali Mortazavi | Developmental & Cell Biology | Genomics, Nextgen sequencing, Chip-seq, ChIA-PET. Cell differentiation, developmental biology |
| Qing Nie | Mathematics, Biomedical Eng. | Numerical mathematics, differential equations, morphogen gradients, stochastic systems |
| Maksim Plikus | Developmental & Cell Biology | Epidermal biology, stem cell biology, hair development and regeneration, |
| Elizabeth Read | Chemical Eng. & Materials Science | Dynamics of complex biochemical systems, regulation of immune responses |
| Thomas Schilling | Developmental & Cell Biology | Development of vertebrate nervous system and skeleton, mathematical models of morphogenesis |
| Albert Siryaporn | Physics | Bacterial pathogenesis at the intersection of biophysics and molecular biology |
| P. Kyle Stanford | Logic & Philosophy of Science | Philosophy of biology, scientific realism, history of developmental and evolutionary biology |
| Peter Taborek | Physics | Mathematics, physics, physical biology, Mathematica software |
| Rahul Warrior | Developmental & Cell Biology | Developmental signaling, growth control, Drosophila genetics |
| Zeba Wunderlich | Developmental & Cell Biology | Evolution of gene regulatory networks, transcriptional control, biophysics, systems biology |
| Xiaohui Xie | Computer Science, Dev. & Cell Biology | Bioinformatics and computational biology, genomics, analysis of high-throughput data sets. |
| JJ Emerson | Ecology and Evolutionary Biology | Bioinformatics and computational biology, evolutionary biology, functional genomics. |
| Elliot Botvinivk | Biomedical Engineering | Biomechanics, Biomedical engineering, Cell Biology, Clinical and Translational Research, Tissue engineering. |
| Jenny Wu | UCI Genomics High-Throughput Facility | Bioinformatics, Genomics |
| Trina Norden-Krichmar | Epidemiology, Pharmaceutical Sciences, Computer Science, Biological Chemistry | Bioinformatics, Genomics |
| Kai Kessenbrock | Biological Chemistry | Cancer, Cell biology, Cell-cell communication |
| Devon Lawson | Physiology and Biophysics | Cancer, Cell biology, Molecular biology |
| Fangyuan Ding | Biomedical Engineering | Quantitative single molecule biology |
| Marcus Seldin | Biological Chemistry | Systems Genetics, Endocrine Physiology, Metabolism, Cell-Cell Communication |
In addition, teaching assistance will be provided by students from UCI’s highly interdisciplinary Mathematical, Computational and Systems Biology graduate program.